|
|
|
|
We compared demographic and clinical features,including outcome defined by a failure time analysis of disability,in 143 patients with a family history of multiple sclerosis(familial MS)compared with 956 patients without such a history(sporadic MS).Patients with familial MS did not differ from those with sporadic MS even when patients with 1st-degree relatives or multiple relatives with MS were considered separately.An intraclass correlation analysis of 13 pairs of affected 1st-degree relatives,both members of which were followed in our clinic,failed to reveal heterogeneity among different families.We were unable to find any support for differences between familial and sporadic MS. |
|